Extracellular Vesicles Derived from Three-Dimensional-Cultured Human Umbilical Cord Blood Mesenchymal Stem Cells Prevent Inflammation and Dedifferentiation in Pancreatic Islets

• Những tác giả chính: Eunwon Lee (Tác giả), Seungyeon Ha (Tác giả), Gyuri Kim (Tác giả), Jae Hyeon Kim (Tác giả), Sang-Man Jin (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2023-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

It is unclear whether extracellular vesicles (EVs) from mesenchymal stem cells (MSCs) have a direct protective effect on pancreatic islets. In addition, whether culturing MSCs in three dimensions (3D) instead of a monolayer (2D) can induce changes in the cargo of EVs that facilitate the polarization...