Prolonged duration of lymphocyte deficiency, high-grade CRS, and ventilation are linked to fungal breakthrough in patients with hematologic malignancies 60 days after CAR-T infusion: A single center case-control study

• Main Authors: Jian Yang (Author), Jinwen Zhang (Author), Jia Wei (Author), Guangjie Wu (Author), Jianxin Song (Author), Dong Liu (Author), Yan He (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Risk factors for invasive fungal infections (IFIs) after chimeric antigen receptor-modified T cells (CAR-T) treatment have been poorly studied. Here we are investigating the risk factors and prognosis of IFIs following CAR-T therapy. Material and Methods: A case-control study was conduct...