Feasibility of transdermal transport of atenolol by combination of iontophoresis and oleic acid pretreatment

• Автори: Akhmad Kharis Nugroho (Автор), Arief Rahman Hakim (Автор), Marlyn Dian Laksitorini (Автор), Fajar Rakhmatullah (Автор), Eny Masruriati (Автор)
• Формат: Книга
• Опубліковано: Universitas Gadjah Mada, 2011-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Atenolol has a low oral bioavailability and a short elimination half-life. Therefore, alternative route and delivery system is important. Transdermal iontophoresis, i.e. a systemic drug delivery via the skin, implementing a low intensity of electrical current, is one attractive candidate. This study...