Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design

• Main Authors: Shaherin Basith (Author), Minghua Cui (Author), Stephani J. Y. Macalino (Author), Jongmi Park (Author), Nina A. B. Clavio (Author), Soosung Kang (Author), Sun Choi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The primary goal of rational drug discovery is the identification of selective ligands which act on single or multiple drug targets to achieve the desired clinical outcome through the exploration of total chemical space. To identify such desired compounds, computational approaches are necessary in p...