Phosphatidylinositol Stabilizes Fluid-Phase Liposomes Loaded with a Melphalan Lipophilic Prodrug

• 主要な著者: Daria Tretiakova (著者), Irina Le-Deigen (著者), Natalia Onishchenko (著者), Judith Kuntsche (著者), Elena Kudryashova (著者), Elena Vodovozova (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Previously, a liposomal formulation of a chemotherapeutic agent melphalan (Mlph) incorporated in a fluid lipid bilayer of natural phospholipids in the form of dioleoylglyceride ester (MlphDG) was developed and the antitumor effect was confirmed in mouse models. The formulation composed of egg phosph...