Timosaponin-BII inhibits the up-regulation of BACE1 induced by Ferric Chloride in rat retina

• Main Authors: Huang Ju-Fang (Author), Shang Lei (Author), Liu Pei (Author), Zhang Meng-Qi (Author), Chen Shuang (Author), Chen Dan (Author), Fan Chun-Ling (Author), Wang Hui (Author), Xiong Kun (Author)
• Format: Book
• Published: BMC, 2012-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Our previous studies indicated that oxidative stress up-regulated the expression of β-amyloid precursor protein cleavage enzyme-1 (BACE1) in rat retina. Pharmacological reports have shown Timosaponin-BII, a purified extract originati...