Development and validation of alternative methods by non-aqueous acid-base titration and derivative ultraviolet spectrophotometry for quantification of sildenafil in raw material and tablets

• Hoofdauteurs: Taízia Dutra Silva (Auteur), Cibele Rodrigues Toledo (Auteur), Cristina Duarte Vianna-Soares (Auteur)
• Formaat: Boek
• Gepubliceerd in: Universidade de São Paulo, 2017-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Sildenafil citrate (SILC) is a potent phosphodiesterase-5 inhibitor used for erectile dysfunction and pulmonary hypertension. This study shows two simple, fast and alternative analytical methods for SILC determination by non-aqueous titration and by derivative ultraviolet spectrophotometry (DUS) in...