A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose

Background and purpose: The study was aimed at validating a simple, rapid, and low-cost LC-MS/MS method for carvedilol and 4/-hydroxyphenyl carvedilol assay in human plasma. The validated method was applied to investigate the pharmacokinetics after a low dose of 6.25 mg. carvedilol. Experimental app...

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Main Authors: Wanna Eiamart (Author), Nantaporn Prompila (Author), Yaowatree Jumroen (Author), Nonlanee Sayankuldilok (Author), Pajaree Chariyavilaskul (Author), Supeecha Wittayalertpanya (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
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