Galectin-1 Facilitates Macrophage Reprogramming and Resolution of Inflammation Through IFN-β

• Main Authors: Hiba Yaseen (Author), Sergei Butenko (Author), Irina Polishuk-Zotkin (Author), Sagie Schif-Zuck (Author), Juan Manuel Pérez-Sáez (Author), Gabriel Adrian Rabinovich (Author), Amiram Ariel (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During the resolution of acute inflammation, macrophages undergo reprogramming from pro-inflammatory, to anti-inflammatory/reparative, and eventually to pro-resolving macrophages. Galectin-1 (Gal-1) is a bona fide pro-resolving lectin while interferon β (IFN-β) was recently shown to facilitate macro...