Testosterone regulates the intracellular bacterial community formation of uropathogenic Escherichia coli in prostate cells via STAT3

• Main Authors: Chen-Hsun Ho (Author), Yu-Chuan Lu (Author), Chia-Kwung Fan (Author), Hong-Jeng Yu (Author), Hsin-Tien Liu (Author), Chia-Chang Wu (Author), Kuan-Chou Chen (Author), Shih-Ping Liu (Author), Po-Ching Cheng (Author)
• Format: Book
• Published: Elsevier, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: UPEC can internalize clonally in prostate to form biofilm-like intracellular bacterial communities (IBCs) for recurrent or chronic infection. We previously indicated that the exposure of prostate cells to testosterone could suppress UPEC invasion and their persistent survival within cell...