A chronic bioluminescent model of experimental visceral leishmaniasis for accelerating drug discovery.

• Main Authors: Raquel Álvarez-Velilla (Author), Maria Del Camino Gutiérrez-Corbo (Author), Carmen Punzón (Author), Maria Yolanda Pérez-Pertejo (Author), Rafael Balaña-Fouce (Author), Manuel Fresno (Author), Rosa María Reguera (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Visceral leishmaniasis is a neglected parasitic disease with no vaccine available and its pharmacological treatment is reduced to a limited number of unsafe drugs. The scarce readiness of new antileishmanial drugs is even more alarming when relapses appear or the occurrence of hard-to-tre...