Re-evaluation of nicotinic acetylcholine receptor in rat brain by a tissue-segment binding assay

• Main Authors: Mao Hsien Wang (Author), Hatsumi eYoshiki (Author), Abu Syed Md Anisuzzaman (Author), Junsuke eUwada (Author), Atsushi eNishimune (Author), Kung Shing Lee (Author), Takanobu eTaniguchi (Author), Ikunobu eMuramatsu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nicotinic acetylcholine receptors (nAChRs) of cerebral cortex and cerebellum of rats were evaluated by a radioligand binding assay, employing tissue segments or homogenates as materials. [3H]-epibatidine specifically bound to nAChRs in rat cortex or cerebellum, but the dissociation constants for [3H...