Evaluation of Adjuvant Activity and Bio-Distribution of Archaeosomes Prepared Using Microfluidic Technology

• Main Authors: Yimei Jia (Author), Gerard Agbayani (Author), Vandana Chandan (Author), Umar Iqbal (Author), Renu Dudani (Author), Hui Qian (Author), Zygmunt Jakubek (Author), Kenneth Chan (Author), Blair Harrison (Author), Lise Deschatelets (Author), Bassel Akache (Author), Michael J. McCluskie (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Archaeosomes, composed of sulfated lactosyl archaeol (SLA) glycolipids, have been proven to be an effective vaccine adjuvant in multiple preclinical models of infectious disease or cancer. They have classically been prepared using a thin-film hydration method with an average particle size of 100-200...