MicroRNA-199a-5p accelerates nucleus pulposus cell apoptosis and IVDD by inhibiting SIRT1-mediated deacetylation of p21

Intervertebral disc degeneration (IVDD) is a multifactorial pathological process associated with low back pain in which nucleus pulposus cell senescence is disrupted. Increasing evidence reveals that IVDD can be modulated by microRNAs (miRNAs or miRs). In the current study, we set out to elucidate t...

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Main Authors: Yiqiang Sun (Author), Xia Wang (Author), Guoyong Fu (Author), Xiaopeng Geng (Author)
Format: Book
Published: Elsevier, 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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