Antiproliferative Copper(II) Complexes Bearing Mixed Chelating Ligands: Structural Characterization, ROS Scavenging, In Silico Studies, and Anti-Melanoma Activity

• Main Authors: Rodica Olar (Author), Catalin Maxim (Author), Mihaela Badea (Author), Mihaela Bacalum (Author), Mina Raileanu (Author), Speranta Avram (Author), Nataša Čelan Korošin (Author), Teodora Burlanescu (Author), Arpad Mihai Rostas (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melanoma is a skin cancer characterized by rapid growth and spread for which current therapies produce both resistance and increased risk of infection. To develop new anti-melanoma biocompatible species, the series of complexes Cu(N-N)(bzac)(X)⋅nH₂O (N-N: 1,10-phenanthroline/2...