Predicting Approximate Clinically Effective Doses in Oncology Using Preclinical Efficacy and Body Surface Area Conversion: A Retrospective Analysis
The correlation between efficacious doses in human tumor-xenograft mouse models and the human clinical doses of approved oncology agents was assessed using published preclinical data and recommended clinical doses. For 90 approved small molecule anti-cancer drugs, body surface area (BSA) corrected m...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2022-04-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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