Small Molecule Palmatine Targeting Musashi-2 in Colorectal Cancer

• Main Authors: Xue Zhang (Author), Kaiyan Su (Author), Yifan Liu (Author), Darong Zhu (Author), Yuting Pan (Author), Xisong Ke (Author), Yi Qu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Musashi-2 (MSI2) is an evolutionally conserved RNA-binding protein and recently considered as an attractive therapeutic target in a wide spectrum of malignancies. However, MSI2-engaged mRNAs are not well profiled, and no MSI2-dependent antagonist is available so far. In the study, we created MSI2 kn...