The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine

• Egile Nagusiak: Qian Wang (Egilea), Jianlin Han (Egilea), Alexander Sorochinsky (Egilea), Aitor Landa (Egilea), Greg Butler (Egilea), Vadim A. Soloshonok (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Nowadays, the selective introduction of fluorine into bioactive compounds is a mature strategy in the design of drugs allowing to increase efficiency, biological half-life and bio-absorption. On the other hand, amino acids (AAs) represent one of the most ubiquitious classes of naturally occurring or...