Biopharmaceutical characterization of topical liposome formulations bearing 5-fluorouracil

• Main Authors: Marija Glavas-Dodov (Author), Emilija Fredro-Kumbaradzi (Author), Sema Calis (Author), Katerina Goracinova (Author), Kristina Mladenovska (Author), Maja Simonoska (Author), Atila A. Hincal (Author)
• Format: Book
• Published: University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association, 2003-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liposome dispersions and liposome gel formulations for topical administration were evaluated as modified release delivery systems for 5-fluorouracil. Drug substance has been entrapped in the internal aqueous compartment of liposomes during the preparation. The concentration of 5-fluorouracil in the...