Identification of exon skipping events associated with Alzheimer's disease in the human hippocampus

• Main Authors: Seonggyun Han (Author), Jason E. Miller (Author), Seyoun Byun (Author), Dokyoon Kim (Author), Shannon L. Risacher (Author), Andrew J. Saykin (Author), Younghee Lee (Author), Kwangsik Nho (Author), for Alzheimer's Disease Neuroimaging Initiative (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background At least 90% of human genes are alternatively spliced. Alternative splicing has an important function regulating gene expression and miss-splicing can contribute to risk for human diseases, including Alzheimer's disease (AD). Methods We developed a splicing decision model as...