New curcumin analog, CCA-1.1, synergistically improves the antiproliferative effect of doxorubicin against T47D breast cancer cells

• Main Authors: Febri Wulandari (Author), Muthi' Ikawati (Author), Dhania Novitasari (Author), Mitsunori Kirihata (Author), Jun-ya Kato (Author), Edy Meiyanto (Author)
• Format: Book
• Published: Universitas Gadjah Mada, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An improved compound of pentagamavunone-1 (PGV-1), chemoprevention-curcumin analog 1.1 (CCA-1.1), has been synthesized and proven to have antiproliferative effects against breast cancer cells. This study is designed to investigate the potency of CCA-1.1 alone and in combination with doxorubicin (Dox...