New curcumin analog, CCA-1.1, synergistically improves the antiproliferative effect of doxorubicin against T47D breast cancer cells

• Autori principali: Febri Wulandari (Autore), Muthi' Ikawati (Autore), Dhania Novitasari (Autore), Mitsunori Kirihata (Autore), Jun-ya Kato (Autore), Edy Meiyanto (Autore)
• Natura: Libro
• Pubblicazione: Universitas Gadjah Mada, 2020-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

An improved compound of pentagamavunone-1 (PGV-1), chemoprevention-curcumin analog 1.1 (CCA-1.1), has been synthesized and proven to have antiproliferative effects against breast cancer cells. This study is designed to investigate the potency of CCA-1.1 alone and in combination with doxorubicin (Dox...