Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents

• Main Authors: Sundas Tariq (Author), Fazal Rahim (Author), Hayat Ullah (Author), Maliha Sarfraz (Author), Rafaqat Hussain (Author), Shoaib Khan (Author), Misbah Ullah Khan (Author), Wajid Rehman (Author), Amjad Hussain (Author), Mashooq Ahmad Bhat (Author), Muhammad Kamran Farooqi (Author), Syed Adnan Ali Shah (Author), Naveed Iqbal (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Benzimidazole-based pyrrole/piperidine analogs (<b>1</b>-<b>26</b>) were synthesized and then screened for their acetylcholinesterase and butyrylcholinesterase activities. All the analogs showed good to moderate cholinesterase activities. Synthesized compounds (<b>1<...