A case of congenital autonomous thyroid adenoma with a somatic activating gene mutation in the thyroid-stimulating hormone receptor
We report here a male case of autonomous adenoma (AA) in the thyroid that was caused by a somatic heterozygous mutation in the thyroid-stimulating hormone receptor (TSHR) gene at codon 453, which encodes the second transmembrane domain of the protein. This activating mutation of TSHR induced an incr...
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Main Authors: | , , , , , , , , , , , |
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Format: | Book |
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Elsevier,
2018-11-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |