Focused Ultrasound-Mediated Delivery of Anti-Programmed Cell Death-Ligand 1 Antibody to the Brain of a Porcine Model

Immune checkpoint inhibitor (ICI) therapy has revolutionized cancer treatment by leveraging the body's immune system to combat cancer cells. However, its effectiveness in brain cancer is hindered by the blood-brain barrier (BBB), impeding the delivery of ICIs to brain tumor cells. This study ai...

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Main Authors: Siaka Fadera (Author), Chinwendu Chukwu (Author), Andrew H. Stark (Author), Yimei Yue (Author), Lu Xu (Author), Chih-Yen Chien (Author), Jinyun Yuan (Author), Hong Chen (Author)
Format: Book
Published: MDPI AG, 2023-10-01T00:00:00Z.
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