(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone

• Main Authors: Antonio Laghezza (Author), Luca Piemontese (Author), Leonardo Brunetti (Author), Alessia Caradonna (Author), Mariangela Agamennone (Author), Fulvio Loiodice (Author), Paolo Tortorella (Author)
• 格式: 图书
• 出版: MDPI AG, 2021-01-01T00:00:00Z.
• 主题: article
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Matrix Metalloproteinases (MMPs) are a family of secreted and membrane-bound enzymes, of which 24 isoforms are known in humans. These enzymes degrade the proteins of the extracellular matrix and play a role of utmost importance in the physiological remodeling of all tissues. However, certain MMPs, s...