Development of a toolkit for piggyBac-mediated integrative transfection of the human filarial parasite Brugia malayi.

• Main Authors: Canhui Liu (Author), Amruta S Mhashilkar (Author), Johan Chabanon (Author), Shulin Xu (Author), Sara Lustigman (Author), John H Adams (Author), Thomas R Unnasch (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The human filarial parasites cause diseases that are among the most important causes of morbidity in the developing world. The elimination programs targeting these infections rely on a limited number of drugs, making the identification of new chemotherapeutic agents a high priority. The s...