Design of expert guided investigation of native L-asparaginase encapsulated long-acting cross-linker-free poly (lactic-co-glycolic) acid nanoformulation in an Ehrlich ascites tumor model

• Main Authors: Manvi Singh (Author), Nazia Hassan (Author), Devina Verma (Author), Pragya Thakur (Author), Bibhu Prasad Panda (Author), Amulya Kumar Panda (Author), Rakesh Kumar Sharma (Author), Aamir Mirza (Author), Sheikh Mansoor (Author), Salman H. Alrokayan (Author), Haseeb A. Khan (Author), Parvaiz Ahmad (Author), Zeenat Iqbal (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Present study explores native L-asparaginase encapsulated long-acting cross-linker-free PLGA-nanoformulation in an Ehrlich ascites tumor model. L-asparaginase-PLGA nanoparticles for tumor were prepared using a double emulsion solvent evaporation technique, optimized and validated by Box-Behnken Desi...