Engineering of Nanofibrous Amorphous and Crystalline Solid Dispersions for Oral Drug Delivery

• Main Authors: Laura Modica de Mohac (Author), Alison Veronica Keating (Author), Maria de Fátima Pina (Author), Bahijja Tolulope Raimi-Abraham (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2018-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Poor aqueous solubility (<0.1 mg/mL) affects a significant number of drugs currently on the market or under development. Several formulation strategies including salt formation, particle size reduction, and solid dispersion approaches have been employed with varied success. In this review, we foc...