Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2<i>H</i>)-one as Novel Scaffold for FABP4 Inhibition

• Hoofdauteurs: Letizia Crocetti (Auteur), Giuseppe Floresta (Auteur), Chiara Zagni (Auteur), Divya Merugu (Auteur), Francesca Mazzacuva (Auteur), Renan Rodrigues de Oliveira Silva (Auteur), Claudia Vergelli (Auteur), Maria Paola Giovannoni (Auteur), Agostino Cilibrizzi (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Fatty acid binding protein (FABP4) inhibitors are of synthetic and therapeutic interest and ongoing clinical studies indicate that they may be a promise for the treatment of cancer, as well as other diseases. As part of a broader research effort to develop more effective FABP4 inhibitors, we sought...