Crotoxin Inhibits Endothelial Cell Functions in Two- and Three-dimensional Tumor Microenvironment

• Main Authors: Ellen Emi Kato (Author), Luciana Araújo Pimenta (Author), Maíra Estanislau Soares de Almeida (Author), Vanessa Olzon Zambelli (Author), Marinilce Fagundes dos Santos (Author), Sandra Coccuzzo Sampaio (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antitumor property of Crotoxin (CTX), the major toxin from Crotalus durissus terrificus snake venom, has been demonstrated in experimental animal models and clinical trials. However, the direct action of this toxin on the significant events involved in neovascularization, which are essential for tum...