Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects

• Main Authors: Beatriz A. Guerra (Author), Bruna B. Brandão (Author), Silas S. Pinto (Author), Willian G. Salgueiro (Author), Evandro A. De-Souza (Author), Felipe C.G. Reis (Author), Thiago M. Batista (Author), Vanessa Cavalcante-Silva (Author), Vânia D'Almeida (Author), Beatriz A. Castilho (Author), Everardo M. Carneiro (Author), Adam Antebi (Author), William T. Festuccia (Author), Marcelo A. Mori (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Dietary restriction (DR) improves health and prolongs lifespan in part by upregulating type III endoribonuclease DICER in adipose tissue. In this study, we aimed to specifically test which missing dietary component was responsible for DICER upregulation. Methods: We performed a nutrient s...