Equilibrium solubility versus intrinsic dissolution: characterization of lamivudine, stavudine and zidovudine for BCS classification

• Main Authors: André Bersani Dezani (Author), Thaisa Marinho Pereira (Author), Arthur Massabki Caffaro (Author), Juliana Mazza Reis (Author), Cristina Helena dos Reis Serra (Author)
• Format: Book
• Published: Universidade de São Paulo, 2013-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Solubility and dissolution rate of drugs are of major importance in pre-formulation studies of pharmaceutical dosage forms. The solubility improvement allows the drugs to be potential biowaiver candidates and may be a good way to develop more dose-efficient formulations. Solubility behaviour of lami...