Equilibrium solubility versus intrinsic dissolution: characterization of lamivudine, stavudine and zidovudine for BCS classification

• Автори: André Bersani Dezani (Автор), Thaisa Marinho Pereira (Автор), Arthur Massabki Caffaro (Автор), Juliana Mazza Reis (Автор), Cristina Helena dos Reis Serra (Автор)
• Формат: Книга
• Опубліковано: Universidade de São Paulo, 2013-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Solubility and dissolution rate of drugs are of major importance in pre-formulation studies of pharmaceutical dosage forms. The solubility improvement allows the drugs to be potential biowaiver candidates and may be a good way to develop more dose-efficient formulations. Solubility behaviour of lami...