A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET

• Main Authors: Hugo Helbert (Author), Emily M. Ploeg (Author), Douwe F. Samplonius (Author), Simon N. Blok (Author), Ines F. Antunes (Author), Verena I. Böhmer (Author), Gert Luurtsema (Author), Rudi A. J. O. Dierckx (Author), Ben L. Feringa (Author), Philip H. Elsinga (Author), Wiktor Szymanski (Author), Wijnand Helfrich (Author)
• Format: Book
• Published: SpringerOpen, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pretargeted immuno-PET tumor imaging has emerged as a valuable diagnostic strategy that combines the high specificity of antibody-antigen interaction with the high signal and image resolution offered by short-lived PET isotopes, while reducing the irradiation dose caused by tradi...