The role of Interleukin-22 in severe acute pancreatitis
Abstract Severe acute pancreatitis (SAP) begins with premature activation of enzymes, promoted by the immune system, triggering a potential systemic inflammatory response that leads to organ failure with increased mortality and a bleak prognosis. Interleukin-22 (IL-22) is a cytokine that may have a...
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Format: | Book |
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BMC,
2024-05-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_9b64dae6efa74cb08d750c1f1cd7710c | ||
042 | |a dc | ||
100 | 1 | 0 | |a Hongli Yang |e author |
700 | 1 | 0 | |a Ruofan Cao |e author |
700 | 1 | 0 | |a Feifei Zhou |e author |
700 | 1 | 0 | |a Ben Wang |e author |
700 | 1 | 0 | |a Qianqian Xu |e author |
700 | 1 | 0 | |a Rui Li |e author |
700 | 1 | 0 | |a ChunHua Zhang |e author |
700 | 1 | 0 | |a Hongwei Xu |e author |
245 | 0 | 0 | |a The role of Interleukin-22 in severe acute pancreatitis |
260 | |b BMC, |c 2024-05-01T00:00:00Z. | ||
500 | |a 10.1186/s10020-024-00826-7 | ||
500 | |a 1528-3658 | ||
520 | |a Abstract Severe acute pancreatitis (SAP) begins with premature activation of enzymes, promoted by the immune system, triggering a potential systemic inflammatory response that leads to organ failure with increased mortality and a bleak prognosis. Interleukin-22 (IL-22) is a cytokine that may have a significant role in SAP. IL-22, a member of the IL-10 cytokine family, has garnered growing interest owing to its potential tissue-protective properties. Recently, emerging research has revealed its specific effects on pancreatic diseases, particularly SAP. This paper provides a review of the latest knowledge on the role of IL-22 and its viability as a therapeutic target in SAP. | ||
546 | |a EN | ||
690 | |a IL -22 | ||
690 | |a Sever acute pancreatitis | ||
690 | |a Inflammation | ||
690 | |a Autophagy | ||
690 | |a SAP-induced multiorgan injury | ||
690 | |a Therapeutics. Pharmacology | ||
690 | |a RM1-950 | ||
690 | |a Biochemistry | ||
690 | |a QD415-436 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024) | |
787 | 0 | |n https://doi.org/10.1186/s10020-024-00826-7 | |
787 | 0 | |n https://doaj.org/toc/1528-3658 | |
856 | 4 | 1 | |u https://doaj.org/article/9b64dae6efa74cb08d750c1f1cd7710c |z Connect to this object online. |