Enhanced Antidepressant Activity of Nanostructured Lipid Carriers Containing Levosulpiride in Behavioral Despair Tests in Mice

• Main Authors: Sadia Tabassam Arif (Author), Muhammad Ayub Khan (Author), Shahiq uz Zaman (Author), Hafiz Shoaib Sarwar (Author), Abida Raza (Author), Muhammad Sarfraz (Author), Yousef A. Bin Jardan (Author), Muhammad Umair Amin (Author), Muhammad Farhan Sohail (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The potential of levosulpiride-loaded nanostructured lipid carriers (LSP-NLCs) for enhanced antidepressant and anxiolytic effects was evaluated in the current study. A forced swim test (FST) and tail suspension test (TST) were carried out to determine the antidepressant effect whereas anxiolytic act...