Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology

SUMMARY Mutations in SEC63 cause polycystic liver disease in humans. Sec63 is a member of the endoplasmic reticulum (ER) translocon machinery, although it is unclear how mutations in SEC63 lead to liver cyst formation in humans. Here, we report the identification and characterization of a zebrafish...

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Main Authors: Kelly R. Monk (Author), Matthew G. Voas (Author), Clara Franzini-Armstrong (Author), Ian S. Hakkinen (Author), William S. Talbot (Author)
Format: Book
Published: The Company of Biologists, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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