Trypanosoma cruzi infection and endothelin-1 cooperatively activate pathogenic inflammatory pathways in cardiomyocytes.

• Váldodahkkit: Ricardo S Corral (Dahkki), Néstor A Guerrero (Dahkki), Henar Cuervo (Dahkki), Núria Gironès (Dahkki), Manuel Fresno (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Trypanosoma cruzi, the causative agent of Chagas' disease, induces multiple responses in the heart, a critical organ of infection and pathology in the host. Among diverse factors, eicosanoids and the vasoactive peptide endothelin-1 (ET-1) have been implicated in the pathogenesis of chronic chag...