Automated Radiosynthesis, Preliminary In Vitro/In Vivo Characterization of OncoFAP-Based Radiopharmaceuticals for Cancer Imaging and Therapy

• Main Authors: Francesco Bartoli (Author), Philip Elsinga (Author), Luiza Reali Nazario (Author), Aureliano Zana (Author), Andrea Galbiati (Author), Jacopo Millul (Author), Francesca Migliorini (Author), Samuele Cazzamalli (Author), Dario Neri (Author), Riemer H. J. A. Slart (Author), Paola Anna Erba (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

FAP-targeted radiopharmaceuticals represent a breakthrough in cancer imaging and a viable option for therapeutic applications. OncoFAP is an ultra-high-affinity ligand of FAP with a dissociation constant of 680 pM. OncoFAP has been recently discovered and clinically validated for PET imaging procedu...