Lysophosphatidylcholine Impairs the Mitochondria Homeostasis Leading to Trophoblast Dysfunction in Gestational Diabetes Mellitus

• Main Authors: Shao-Chi Hung (Author), Te-Fu Chan (Author), Hsiu-Chuan Chan (Author), Chia-Ying Wu (Author), Mei-Lin Chan (Author), Jie-Yang Jhuang (Author), Ji-Qin Tan (Author), Jia-Bin Mei (Author), Shi-Hui Law (Author), Vinoth Kumar Ponnusamy (Author), Hua-Chen Chan (Author), Liang-Yin Ke (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gestational diabetes mellitus (GDM) is a common pregnancy disorder associated with an increased risk of pre-eclampsia and macrosomia. Recent research has shown that the buildup of excess lipids within the placental trophoblast impairs mitochondrial function. However, the exact lipids that impact the...