M2c Macrophages Protect Mice from Adriamycin-Induced Nephropathy by Upregulating CD62L in Tregs

• Main Authors: Junyu Lu (Author), Shengqiu Lv (Author), Jielong Pang (Author), Tao Qin (Author), Yegui Yang (Author), Weisheng Lu (Author), Zhengzhao Li (Author), Geng Yang (Author), Jianfeng Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Regulatory T cells (Tregs) and M2c macrophages have been shown to exert potentially synergistic therapeutic effects in animals with adriamycin-induced nephropathy (AN), a model chronic proteinuric renal disease. M2c macrophages may protect against renal injury by promoting an increase in the number...