Functional profiling of CHAP domain-containing peptidoglycan hydrolases of Staphylococcus aureus USA300 uncovers potential targets for anti-staphylococcal therapies

• Main Authors: Min Wang (Author), Xiaofang Li (Author), Francis M. Cavallo (Author), Harita Yedavally (Author), Sjouke Piersma (Author), Elisa J.M. Raineri (Author), Elias Vera Murguia (Author), Jeroen Kuipers (Author), Zhenhua Zhang (Author), Jan Maarten van Dijl (Author), Girbe Buist (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The bacterial pathogen Staphylococcus aureus employs a thick cell wall for protection against physical and chemical insults. This wall requires continuous maintenance to ensure strength and barrier integrity, but also to permit bacterial growth and division. The main cell wall component is peptidogl...