The effect of (-)-epigallocatechin 3-O--gallate in vitro and in vivo in Leishmania braziliensis: involvement of reactive oxygen species as a mechanism of action.

• Main Authors: Job D F Inacio (Author), Luiza Gervazoni (Author), Marilene M Canto-Cavalheiro (Author), Elmo E Almeida-Amaral (Author)
• 格式: 图书
• 出版: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Leishmaniasis is a parasitic disease associated with extensive mortality and morbidity. The treatment for leishmaniasis is currently based on pentavalent antimonials and amphotericin B; however, these drugs result in numerous adverse side effects. Natural compounds have been used as novel treatments...