Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia

• Hauptverfasser: Hongyang Xu (Verfasst von), Rojina Ranjit (Verfasst von), Arlan Richardson (Verfasst von), Holly Van Remmen (Verfasst von)
• Format: Buch
• Veröffentlicht: Wiley, 2021-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Oxidative stress and damage are associated with a number of ageing phenotypes, including age‐related loss of muscle mass and reduced contractile function (sarcopenia). Our group and others have reported loss of neuromuscular junction (NMJ) integrity and increased denervation as i...