Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer

• Main Authors: Ying Liu (Author), Zan Song (Author), Yajie Liu (Author), Xubin Ma (Author), Wang Wang (Author), Yu Ke (Author), Yichao Xu (Author), Dequan Yu (Author), Hongmin Liu (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is a type of cell death accompanied by iron-dependent lipid peroxidation, thus stimulating ferroptosis may be a potential strategy for treating gastric cancer, therapeutic agents against which are urgently required. Jiyuan oridonin A (JDA) is a natural compound isolated from Jiyuan Rabdo...