CFTR Modulator Therapy Enhances Peripheral Blood Monocyte Contributions to Immune Responses in People With Cystic Fibrosis

• Main Authors: Katherine B. Hisert (Author), Timothy P. Birkland (Author), Kelly Q. Schoenfelt (Author), Matthew E. Long (Author), Brenda Grogan (Author), Suzanne Carter (Author), W. Conrad Liles (Author), Edward F. McKone (Author), Lev Becker (Author), Anne M. Manicone (Author), Sina A. Gharib (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundCFTR modulators decrease some etiologies of CF airway inflammation; however, data indicate that non-resolving airway infection and inflammation persist in individuals with CF and chronic bacterial infections. Thus, identification of therapies that diminish airway inflammation without allow...