Thalidomide promotes leukocytosis in mice inoculated with 4T1 mammary carcinoma

• Main Authors: Diego Carlos dos Reis (Author), Cristina Maria de Souza (Author), Liliane Cunha Campos (Author), Ana Cândida Araújo e Silva (Author), Miriam Teresa Paz Lopes (Author), Geovanni Dantas Cassali (Author), Enio Ferreira (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to evaluate the therapy effect of thalidomide in the 4T1 murine mammary carcinoma. 4T1 cell suspension was injected into the posterior left flank of all animals to obtain solid tumors. Five days after inoculation, the treatment group was orally administered 150 mg/kg of tha...