Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels)

• Main Authors: Izabela Szymczak-Pajor (Author), Józef Drzewoski (Author), Ewa Świderska (Author), Justyna Strycharz (Author), Anna Gabryanczyk (Author), Jacek Kasznicki (Author), Marta Bogdańska (Author), Agnieszka Śliwińska (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Accumulating evidence (mainly from experimental research) suggests that metformin possesses anticancer properties through the induction of apoptosis and inhibition of the growth and proliferation of cancer cells. However, its effect on the enzymes responsible for histone acetylation status, which pl...