Hydrogen Peroxide Is Responsible for the Cytotoxic Effects of Streptococcus pneumoniae on Primary Microglia in the Absence of Pneumolysin
Introduction: Streptococcus pneumoniae is the most common cause of bacterial meningitis and meningoencephalitis in humans. The bacterium produces numerous virulence determinants; among them, hydrogen peroxide (H2O2) and pneumolysin (Ply) contribute to bacterial cytotoxicity. Microglia, the resident...
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Main Authors: | Franziska Jennert (Author), Désirée Schaaf (Author), Roland Nau (Author), Thomas P. Kohler (Author), Sven Hammerschmidt (Author), Darius Häusler (Author), Peter Valentin-Weigand (Author), Jana Seele (Author) |
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Format: | Book |
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Karger Publishers,
2024-04-01T00:00:00Z.
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